Portable · Disinfectable · Multispectral Imaging for Biological Research
Product Overview
The Multicolor Illumination and Disinfectable Smartphone Imager is a compact and versatile imaging platform designed for biological tissue observation, small animal imaging, and educational laboratory applications.
The system integrates:
(1) A waterproof smartphone enclosure with a high-transparency optical window
(2) A universal adjustable stand
(3) A multicolor waterproof LED illumination module
(4) A stable optical breadboard base
An optional graded, temperature-controlled animal surgery platform can be added for physiological or microsurgical procedures.
This system transforms a standard smartphone into a hygienic, multispectral imaging device, ideal for biological research environments where sterilization and optical precision are essential.
Key Features
1. Disinfectable Smartphone Enclosure
(1)Waterproof design with optical-grade transparent window
(2) Fully sealed housing allows direct disinfection with 70% alcohol or sterile wipes
(3) Protects smartphone against moisture and contamination without compromising image quality
2. Multicolor Waterproof LED Light Source
(1) Selectable wavelengths for optimized imaging contrast:
Blue (470 nm): Highlights superficial vasculature and epidermal texture
Green (530 nm): Enhances visualization of hemoglobin and blood flow
Red (625 nm): Penetrates deeper tissue layers, revealing dermal contours
White (6500 K): Broad-spectrum illumination for standard imaging
(2) Safe for alcohol disinfection and wet-lab environments
3. Modular Optical Platform
(1) Optical breadboard base ensures mechanical stability and system expandability
(2) Compatible with various optical components and clamps
(3) Facilitates secure fixation of samples and animal platforms
4. Temperature-Controlled Animal Platform (Optional)
(1) Waterproof, disinfectable surface for easy cleaning
(2) Integrated graphene-based heating and feedback control
(3) Provides uniform and stable temperature to maintain small animal body heat during extended imaging sessions
Imaging Enhancement
Multispectral and RGB Illumination Benefits
In the absence of a spectrometer, RGB-based multispectral illumination enables clear visualization of tissue features through wavelength-dependent absorption and scattering properties:
Blue light: Emphasizes capillaries and surface texture
Green light: Reveals oxygenated and deoxygenated blood regions
Red light: Penetrates deeper layers for subdermal imaging
Advanced image reconstruction methods such as PCA, ICA, or pseudo-color mapping further enhance contrast and reveal layer-specific structural information.
Optical Principle
|
Wavelength Range |
Dominant Absorbers |
Penetration Depth |
Imaging Characteristics |
|
UV (300–400 nm) |
Nucleic acids, aromatic amino acids |
<100 μm |
Surface, corneal, epithelial imaging |
|
Blue (430–490 nm) |
Hemoglobin, melanin |
0.5–1 mm |
Vascular and epidermal contrast |
|
Green (500–560 nm) |
Hemoglobin |
1–2 mm |
Blood oxygenation visualization |
|
Red (600–700 nm) |
Collagen, muscle tissue |
2–5 mm |
Deep tissue imaging, reduced hemoglobin absorption |
|
NIR (700–1000 nm) |
Water, fat, collagen |
Several cm |
Subsurface and internal tissue imaging |
Applications
(1) Biological tissue imaging and spectroscopy
(2) Small animal microsurgery and physiology monitoring
(3) Educational demonstrations in anatomy and biophotonics
(4) Portable laboratory imaging in field or clinical research settings
(5) Optical material studies and fluorescence inspection
Technical Specifications
|
Component |
Description |
|
Illumination |
Multicolor waterproof LED (Blue 470 nm, Green 530 nm, Red 625 nm, White 6500 K) |
|
Light Control |
Manual LED channel switching |
|
Smartphone Enclosure |
Waterproof, transparent optical-grade window |
|
Platform Base |
Optical breadboard with M6 grid holes |
|
Adjustable Stand |
Multi-axis articulated arm with sample clamps |
|
Temperature Platform (Optional) |
Graphene heater, PID-controlled (±0.5 °C accuracy) |
|
Disinfection Method |
70% alcohol spray or sterilizing wipes |
Conclusion
The Multicolor Illumination and Disinfectable Smartphone Imager provides a safe, flexible, and high-contrast imaging solution that leverages everyday smartphone technology for advanced biological visualization.
Its multispectral illumination, optical stability, and fully disinfectable design make it an ideal tool for biomedical research, veterinary studies, and educational training environments.
References
(1) Donghak Lee, Suho Ryu, Uihan Kim, Daeseong Jung, and Chulmin Joo, “Color‑coded LED microscopy for multi‑contrast and quantitative phase‑gradient imaging,” Biomed. Opt. Express 6, 4912–4922 (2015).
(2) Xiaojun Wu and Guangming Gao, “LED light design method for high contrast and uniform illumination imaging in machine vision,” Appl. Opt. 57, 1694–1704 (2018).
(3) H. Zhang, Y. Hu, X. Pu, S. Zhang, Y. He, K. Chen, and Z. Liu, “LED‑based multicolor extended resolution transmission fluorescence microscopy,” J. Biomed. Opt. 30, 046501 (2025).